Neurofibrillary Tangles (NFTs) are aggregates of hyperphosphorylated tau protein that are most commonly known as a primary marker of Alzheimer`s Disease. Their presence is also found in numerous other diseases known as tauopathies. Little is known about their exact relationship to the different pathologies. ==Formation== Neurofibrillary tangles a....
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http://en.wikipedia.org/wiki/Neurofibrillary_tangle
(from the article `Alzheimer disease`) The presence of neuritic plaques and neurofibrillary tangles in the brain are used to diagnose Alzheimer disease in autopsy. Neuritic plaques—also ... ...neuropeptide molecules that transmit signals between nerve cells. Two other characteristic tissue lesions found in the cerebral cortex of pa...
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http://www.britannica.com/eb/a-z/n/29
<cell biology> Accumulation of twisted protein fragments inside nerve cells. Neurofibrillary tangles are one of the characteristic structural abnormalities found in the brains of patients with Alzheimer's disease patients. ... Upon autopsy, the presence of neuritic plaquesand neurofibrillary tangles is used to positively diagnose Alzheimer's ...
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http://www.encyclo.co.uk/local/20973
Pathological clusters of the protein tau that are found within neurons.
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http://www.encyclo.co.uk/local/22236
A characteristic pathological feature of the brain of patients with Alzheimer&`s disease is the presence of tangles of coarse neurofibrils within large neurons of the cerebral cortex. Whether this causes neuronal degeneration or is a secondary consequence remains contentious.
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Type: Term Definitions: 1. intraneuronal accumulations of helical filaments that assume twisted contorted patterns; found in cells of the hippocampus and cerebral cortex in patients with Alzheimer disease.
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http://www.medilexicon.com/medicaldictionary.php?t=89655
An accumulation of twisted protein (tau protein) fragments inside nerve cells. Neurofibrillary tangles are one of the characteristic structural abnormalities found in the brains of people with Alzheimers disease. Upon autopsy, the presence of amyloid plaques and neurofibrillary tangles is used to positively diagnose Alzheimers disease.
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https://www.encyclo.co.uk/local/23246
No exact match found.
